| CASE REPORT |
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| Year : 2016 | Volume
: 6
| Issue : 3 | Page : 155-157 |
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Candida parapsilosis keratitis treated successfully with topical and oral fluconazole
Pei-Hsuan Li1, Chun-Chen Chen2, Shiow-Wen Liou3
1 Department of Ophthalmology, Taipei City Hospital Renai Branch, Taipei, Taiwan
2 Department of Ophthalmology, Taipei City Hospital Renai Branch; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan
3 Department of Ophthalmology, Taipei City Hospital Renai Branch; Department of Ophthalmology, National Taiwan University Hospital; Taipei Medical University, Taipei, Taiwan
Correspondence Address:
Chun-Chen Chen
Department of Ophthalmology, Taipei City Hospital Renai Branch; Institute of Clinical Medicine, National Yang-Ming University, Taipei
Taiwan
 Source of Support: None, Conflict of Interest: None  | 4 |
DOI: 10.1016/j.tjo.2016.04.007
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A 73-year-old male patient presented with ocular pain, redness, and blurred vision in the left eye, which had been ongoing for more than 2 months. An oval-shaped paracentral corneal ulcer with stromal infiltration and a mild anterior chamber reaction were found. Despite treatment with empiric antibiotics, the lesion progressed and corneal thinning in the middle area was noted. The culture yielded Candida parapsilosis. We therefore prescribed topical 0.2% fluconazole (FCZ) in combination with oral FCZ as an antifungal treatment, following which the stromal infiltration gradually subsided. Complete epithelial-ization was noted on the 8th day after initiating FCZ therapy. There was no recurrent disease in the subsequent 2 years. Our case demonstrates that topical FCZ 0.2% in combination with oral FCZ can successfully treat C. parapsilosis keratitis and result in a good visual outcome.
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