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Year : 2023  |  Volume : 13  |  Issue : 1  |  Page : 93-96

Herpes endotheliitis following laser-assisted in situ keratomileusis and photorefractive keratectomy

1 Hoopes Vision Research Center, Hoopes Vision, Draper; John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City; Utah Lions Eye Bank, Murray, UT, USA
2 University of Texas Health Science Center, McGovern Medical School, Houston, TX, USA
3 University of Utah School of Medicine, Salt Lake City, UT, USA
4 University of Arizona College of Medicine - Phoenix, Phoenix, AZ, USA
5 Hoopes Vision Research Center, Hoopes Vision, Draper, UT, USA

Correspondence Address:
Dr. Majid Moshirfar
Hoopes Vision Research Center, 11820 S. State St. #200, Draper, UT 84020
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/tjo.TJO-D-22-00156

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Herpes endotheliitis is a less common manifestation of herpes keratitis, and characteristic examination findings include corneal edema and the presence of keratic precipitates. Infection may be primary or secondary to herpes virus reactivation following exposure to a potential trigger such as physiologic stress or environmental factors. Ocular surgery, including laser-assisted in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK), can trigger reactivation in patients with or without a documented history of previous herpes infection. We present two patients with visually insignificant stromal scarring who denied a previous history of herpetic disease and developed herpes endotheliitis following LASIK and PRK. We demonstrate the importance of an appropriately thorough preoperative evaluation and further workup of any corneal abnormalities, even if such findings initially appear inconsequential.

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