• Users Online: 386
  • Print this page
  • Email this page
 
CASE REPORT
Ahead of Print

Intravitreal aflibercept combined with transpupillary thermotherapy in the treatment of refractory macular edema due to primary uveal melanoma


1 Department of Ophthalmology, China Medical University Hospital, China Medical University, Taichung, Taiwan
2 Department of Ophthalmology, China Medical University Hospital, China Medical University; School of Medicine, College of Medicine, China Medical University; Department of Optometry, Asia University, Taichung, Taiwan
3 Department of Ophthalmology, China Medical University Hospital, China Medical University, Taichung, Taiwan; Stanford University School of Medicine, Stanford, California, USA

Correspondence Address:
Chun-Ju Lin,
Department of Ophthalmology, 2 Yuh-Der Road, Taichung 40447
Taiwan
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/tjo.tjo_44_21

We reported a 74 year old Asian female with a uveal tumor with subretinal fluid (SRF) and cystoid macula edema. Since she declined biopsy, multimodal imaging study was performed, including fundus photography, ultrasonography, optical coherence tomography, fluorescein angiography, and magnetic resonance imaging. Uveal melanoma was diagnosed. However, despite aggressive treatment with TTT and three adjuvant intravitreal bevacizumab doses, SRF, and cystoid macula edema were persistent. Therefore, aflibercept was administered, resulting in anatomical and functional improvement within 1 month, which lasted for 12 months. Aflibercept offered great efficacy in improving refractory macular edema in this case of primary uveal melanoma. Multimodal imaging can provide us with more diagnostic clues in differentiating the nature of intraocular tumors.


Print this article
Search
 Back
 
  Search Pubmed for
 
    -  Huang YT
    -  Lin CJ
    -  Hsia NY
    -  Lai CT
    -  Bair H
    -  Tsai YY
 Citation Manager
 Article Access Statistics
 Reader Comments
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed272    
    PDF Downloaded3    

Recommend this journal