• Users Online: 165
  • Print this page
  • Email this page
 
REVIEW ARTICLE
Ahead of Print

Primary congenital glaucoma: We are always on the way


1 Department of Ophthalmology and Visual Science, Eye and ENT Hospital, Shanghai Medical College, Fudan University; NHC Key Laboratory of Myopia, Chinese Academy of Medical Sciences, and Shanghai Key Laboratory of Visual Impairment and Restoration (Fudan University), Shanghai, China
2 Department of Ophthalmology and Visual Science, Eye and ENT Hospital, Shanghai Medical College, Fudan University; NHC Key Laboratory of Myopia, Chinese Academy of Medical Sciences, and Shanghai Key Laboratory of Visual Impairment and Restoration (Fudan University); State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

Correspondence Address:
Xinghuai Sun,
No. 83, Road Fenyang, Xuhui District, Shanghai 200031
China
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2211-5056.363178

Primary congenital glaucoma (PCG), a developmental glaucoma occurring due to angle anomaly, earns growing concerns among ophthalmologists for its vision-damaging attribute. The incidence of PCG varies among races and geographic regions and is mostly genetically associated. Theories have been posed in attempt to address the etiology of this congenital maldevelopment and in the meanwhile providing evidence for feasibility of PCG surgeries. In regard to the clinical aspects of this entity, both the clinical characteristics and general principals of management are introduced, with angle surgeries highlighted for clarifying details including their success rates, key points for a successful surgical intervention, postoperative management, and follow-up strategies. Taking patients' vision-associated quality of life into consideration, we stressed that further perceptual learning and low vision rehabilitation are momentous. However, much has yet to be elucidated in respect of the truly comprehensive pathogenesis underneath as well as means by which clinical outcomes of PCG can be further improved. We are now looking forward to innovative therapeutic approaches like gene therapy in specific genes in the future, with the hope of improving their life-long visual quality in those young patients.


Print this article
Search
 Back
 
  Search Pubmed for
 
    -  Yang H
    -  Lu W
    -  Sun X
 Citation Manager
 Article Access Statistics
 Reader Comments
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed173    
    PDF Downloaded3    

Recommend this journal