Year : 2022 | Volume
: 12 | Issue : 4 | Page : 430--436
Structural and functional outcomes of pars plana vitrectomy in patients with lamellar macular hole
Alireza Khodabande, Hamid Riazi-Esfahani, Hafez Ghassemi, Arash Mirzaei, Haider Abbas, Masoud Mirghorbani
Department of Ophthalmology, Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
PURPOSE: To investigate the short-term functional and microstructural outcomes of pars plana vitrectomy (PPV) without gas tamponade in lamellar macular holes (LH).
MATERIALS AND METHODS: In this prospective case series, LH cases diagnosed by optical coherence tomography (OCT) underwent PPV with epiretinal membrane (ERM) removal and internal limiting membrane peeling without gas tamponade. All patients underwent a complete ophthalmologic examination, including best-corrected visual acuity (BCVA) and OCT imaging preoperatively and 3 months after the surgery.
RESULTS: Among 22 eyes, 10 degenerative (Deg) LH, 8 tractional (Trac) LH, and 4 mixed-type LH were assessed. After the surgery, anatomical closure occurred in 20 eyes (91%) without any significant difference between LH subgroups. Comparing preoperative and postoperative values, no significant changes was detected regarding BCVA neither totally (P = 0.5) nor in subgroups (P for Deg = 1.0, Trac = 0.71, Mix = 0.18). The overall central foveal thickness was increased significantly after surgery (P < 0.01), but in subgroup analysis, the increase was significant only for Trac LH (P = 0.02). The tractional LH eyes had less ellipsoid zone (EZ) disruptions compared to Deg or mixed subgroups before surgery. There were no changes in EZ integrity before and after the surgery. In regression analysis, no correlation was found between demographic or clinical characteristics and anatomical closure or BCVA improvement postoperatively.
CONCLUSION: PPV resulted in 91% anatomical closure of all cases of LH but without functional improvement in short-term. Further prospective clinical trials with larger sample size and longer follow-up would be required to confirm the clinical significance of these findings.
Dr. Arash Mirzaei
Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Science, Tehran
|How to cite this article:|
Khodabande A, Riazi-Esfahani H, Ghassemi H, Mirzaei A, Abbas H, Mirghorbani M. Structural and functional outcomes of pars plana vitrectomy in patients with lamellar macular hole.Taiwan J Ophthalmol 2022;12:430-436
|How to cite this URL:|
Khodabande A, Riazi-Esfahani H, Ghassemi H, Mirzaei A, Abbas H, Mirghorbani M. Structural and functional outcomes of pars plana vitrectomy in patients with lamellar macular hole. Taiwan J Ophthalmol [serial online] 2022 [cited 2023 Apr 2 ];12:430-436
Available from: https://www.e-tjo.org/article.asp?issn=2211-5056;year=2022;volume=12;issue=4;spage=430;epage=436;aulast=Khodabande;type=0